Saturday, 6 April 2013

Resolution of Brain Mystery - Prospects!


Resolution of Brain Mystery - Prospects!

Summary: Obama administration recently announced its plan to fund brain mapping project expressing the hope that this project will demystify human brain. However certain doubts are expressed herein and it is suggested that comprehensive interpretation of existing data is the first step in the right direction.
I recently came to know about brain mapping project of Obama Administration.

I wish to state that brain is not a static structure. It has relatively stable structural elements and variable structural elements. So brain mapping can provide us better information about relatively fixed structural elements but may not be of much help as far as variable structural elements are concerned. It may provide us no clue to why and how variable structural elements vary. So a research primarily directed at brain mapping is likely to leave brain as enigmatic as ever.

Therefore brain mapping will enhance understanding of brain structure and function but in a limited way.

The situation is analogous to gene mapping project which has not led to comprehensive understanding of gene expression.

The root cause of this difficulty is that Physicists are not willing to think beyond matter and energy and Biologists are not willing to think beyond Darwin.

In my book "Encounter of Science and Philosophy - A Synthetic View" (http://sciencengod.com/)I have stated that to understand gene expression we have to move beyond molecular anatomy of gene into the domain of natural computing which in turn is material expression of consciousness that permeates this universe.

Likewise in the domain of brain we need to recognize goal directed functioning of brain with a view to keep identity and integrity of an individual with the help of natural computing which manifests as molecular computing etc.

Until and unless research is carried out with the right perspective, data hunting alone will be insufficient to meet research objectives. Even as on date voluminous amount of data exists which requires comprehensive interpretation in the light of above stated observations.

Therefore comprehensive interpretation of available data should receive a priority over further data hunting. However once comprehensive interpretation of available data is available, than it can be used to guide further research using the most advanced techniques as per the needs.
Author: Dr Mahesh C. Jain is a practicing medical doctor has written the book “Encounter of Science with Philosophy – A synthetic view”. The book begins with first chapter devoted to scientifically valid concept of God and then explains cosmic phenomena right from origin of nature and universe up to origin of life and evolution of man. The book includes several chapters devoted to auxiliary concepts and social sciences as corollaries to the concept of God. Consciousness is one of the aspects of and had to precede origin of universe. This is the only book which deals with origin of nature and universe from null or Zero or nothing.
Visit:http:// www.sciencengod.com
          http://www.sciencengod.com/clipboard.htm
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Tuesday, 26 February 2013

Why Big Bang is Implausible



Why Big Bang is Implausible
Summary: Big Bang theory is the most widely accepted cosmological model. It has been widely claimed that it is well supported by evidence. However it is found that it is only a convenient explanation for several observations but the assumptions underlying Big Bang theory are neither supported by independent evidence nor meet the test of plausibility. Big Bang theory and observations explained by it are the only evidence in support of assumptions underlying Big Bang theory. Moreover alternative explanations to the same observations do exist but they have not been duly considered so far.
The big theory in brief is as under (Ref: Wikipedia):-
The Big Bang theory is the prevailing cosmological model that describes the early development of the Universe.  According to the theory, the Big Bang occurred approximately 13.77 billion years ago, which is thus considered the age of the universe. After this time, the Universe was in an extremely hot and dense state and began expanding rapidly. After the initial expansion, the Universe cooled sufficiently to allow energy to be converted into various subatomic particles, including protons, neutrons, and electrons. Though simple atomic nuclei could have formed quickly, 3, 79,000 years were needed before the appearance of the first electrically neutral atoms. The first element produced was hydrogen, along with traces of helium and lithium. Giant clouds of these primordial elements later coalesced through gravity to form stars and galaxies, and the heavier elements were supposed to have been synthesized either within stars or during supernovae.
The Big Bang is the most widely accepted theory within the scientific community. Evidence in its support include the abundance of light elements, the cosmic microwave background, large scale structure, and the Hubble diagram for Type Ia supernovae. The core ideas of the Big Bang—the expansion, the early hot state, the formation of helium, and the formation of galaxies—are derived from these and other observations that are independent of any cosmological model. As the distance between galaxy clusters is increasing today, it is inferred that everything was closer together in the past.
Quite often straight line logical interpretation of available evidence gives rise to theories which are nothing more than a convenient summary of observations. However the only reasonable approach would be examining consistency of such theories with large number of well established facts and natural laws embracing the theory. Karl R. Popper has rightly said that theories can’t be proved on the basis of evidence alone. A single observation contradicting the theory is sufficient to disprove the theory. A theory has also to be tested on the basis of Plausibility Principle which means that for a theory to be true and correct, it has to be plausible with all laws and things embracing it. Hertz observed that Maxwell’s Equations have been accepted on the basis of Plausibility Principle, since the underlying logic was difficult to understand.
Further same set of facts can give rise to multiple theories and then all the competing theories have to be differentiated against each other on all possible parameters to arrive at the most acceptable theory.
Big Bang theory is implausible on the following among other grounds:-
1. No explanation is provided about source of dense matter.
2. There is no answer to the question “What exactly is/was dense matter?”
3. What is the independent evidence supporting existence of dense matter?
4. What precipitated Big Bang in the so called dense matter?
5. How was the pre Big Bang Universe filled with an incredibly high energy density,homogeneously and isotropically with huge temperatures  and pressures?
6. What is the source of this energy?
7. What exactly is high energy density and what independent evidence supports its existence?
8. In the pre Big Bang universe laws of physics did not apply. So was it a total chaos or some other set of laws applied. If later was the case than what were the laws applicable to pre Big Bang universe?
9. How can subatomic particles keep their independent existence for           3, 79,000 years when this is not normally known to happen?
10. How Big Bang led to a universe organized on the basis of laws of physics?
11. What is the source of laws of Physics in the absence of external interference?
12. Can’t the evidence in support of Big Bang theory be explained on the basis of the assumption that universe keeps getting created all the time and hence keeps expanding under the conditions even now prevalent. So no extraordinary conditions are required for creation and expansion of universe. The natural laws that operated in the beginning are operative even now and shall remain operative in future as well?
13. How could giant clouds of primordial elements coalesce through gravity to form stars and galaxies?
14. How is observed diversity in elemental composition of planets and stars consistent with Big Bang Theory?
In brief Big Bang Theory as an explanation of origin of universe is quite implausible when examined on the basis of Plausibility Principle.
Author: Dr Mahesh C. Jain is a practicing medical doctor has written the book “Encounter of Science with Philosophy – A synthetic view”. The book begins with first chapter devoted to scientifically valid concept of God and then explains cosmic phenomena right from origin of nature and universe up to origin of life and evolution of man. The book includes several chapters devoted to auxiliary concepts and social sciences as corollaries to the concept of God. Consciousness is one of the aspects of and had to precede origin of universe. This is the only book which deals with origin of nature and universe from null or Zero or nothing.
Visit:http:// www.sciencengod.com
          http://www.sciencengod.com/clipboard.htm
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Monday, 18 February 2013

Can any Law ever be Absolute


Can any Law ever be Absolute
Summary: Applicability of any law is limited by nature and context of things and events. Therefore no law can ever be absolute. 
Legal systems have their origin in dissatisfaction resulting from individualistic and subjective interpretation of facts and circumstances. Individualistic and subjective interpretation of facts and circumstances often led to irreconcilable and even mutually contradictory differences between different interpretations of same set of facts and circumstances by different individuals at the same time. Even interpretations by the same individual of similar set of facts and circumstances at different times were found inconsistent, irreconcilable and mutually contradictory. This can often be observed even in the contemporary society when things and events are judged without applying standardized yardsticks. Morally unscrupulous people often vary their yardstick from one set of circumstances to another. They can often be seen protecting things, events and people they are interested in and abusing the rest. They resent any call for use of appropriate standardized criterion. For them only criterion are their interest, comfort, convenience and their authority.
So naturally a need to evolve standardized criterion for evaluation of facts and circumstances and determining subsequent course of action was strongly felt. This eventually gave rise to law based system of governance in which laws were elevated to the level of gospel truth. Courts and legislatures were entrusted with the task of determining applicable laws. All this was done and has been practiced without any understanding of what is law. An approval by court of law or legislature was sufficient to elevate any condition to the status of its being a law. There was no need to explain rationale behind any particular law on the basis of natural course of events. For example during the last century relationship between a doctor and patient was reduced to a contractual relationship between a service provider and service recipient with a patient having all the rights and authority of a consumer. So by the stroke of a judicial pen the age old relationship of trust was reduced to a commercial relationship. No consideration was paid to intrinsic nature of relationship, dependence of patients on the skills and knowledge of their doctors for their welfare and ability of patients to appropriately use the legally conferred authority. Numerous instances of legally perpetuated social imbalances are on record. Even judicial interpretation of same set of laws is known to vary from time to time.
In formulation of laws governing any society, natural course of events has often been ignored. Terms, conditions, procedures etc. which should not have been defined as law have been defined as law. This has introduced legally perpetuated chaotic elements incidental to human living. Not only chaos, in many situations “might is the right” is the only law that prevails.
Even in nature a law is a mandatory condition that has to be satisfied to meet specified goals and objectives. For example to call a piece of matter as living matter it has to satisfy all mandatory conditions that are incidental to life. Therefore, howsoever diverse organisms may be and whatever may be their conditions of existence, an organism can exist as living being only if it is able to meet all the mandatory conditions necessary for being alive.
However, nature is hierarchically organized and applicable rules vary from one hierarchical level to another. Moreover different contexts or set of circumstances may also make it obligatory to meet specified goals and objectives in different ways. Therefore formulation and applicability of any law is limited by nature and context of things and events. Hence no law can ever be absolute.
Author: Dr Mahesh C. Jain is a practicing medical doctor and has written the book “Encounter of Science with Philosophy – A synthetic view”. The book begins with first chapter devoted to scientifically valid concept of God and then explains cosmic phenomena right from origin of nature and universe up to origin of life and evolution of man. The book includes several chapters devoted to auxiliary concepts and social sciences as corollaries to the concept of God. This is the only book which deals with origin of nature and universe from null or Zero or nothing. Chapter – 34 of the book defines law, describes chief characteristics of law and identifies some general laws of nature. 
http://curatio.in

Tuesday, 12 February 2013

Human Relationships: Nature and Challenges


Human Relationships: Nature and Challenges
Summary: In the entire biosphere mankind observes most diverse range of relationships. Relationships are intrinsic to human needs. Relationships are governed by specific rules underlying particular relationships. On one hand relationships are a human need and on the other hand relationships are liable to abuse. Therefore for our emotional and physical well-being we need to wisely manage our relationships.
We humans live through a variety of relationships. Vast range of relationships we live through is unique to mankind. No other species needs or observes so many different relationships and in such diverse ways. Diversity of relationships is intrinsic to human nature. There are many other species known to live in groups but do not have relationships differentiated into mother, father, daughter, sister, brother, spouse, grandparents etc. For example lions are known to live in groups but the only relationship lions recognize is male female relationship with the dominant male lion having mating rights over females of the group irrespective of historical considerations.
Diversity of relationships is intrinsic to human nature, as can be seen in the most primitive tribal societies as well as the most advanced human societies. Relationships can be broadly divided into two groups i.e. congenital and acquired. Congenital relationships may also be designated as inherited or historical relationships being determined by birth. Acquired relationships can be further divided into social relationships and friendships. Social relationships may be determined by matrimonial relationship or place of residence, education and work. Friendships are the relationships of our own choice generally determined by companionship and mutual commitment. Friendship is more than meeting of interest or acquaintance. It implies emotional bonding and mutual concern.
All relationships are dynamic in character. Dynamism is more in the case of social relations and friendships. Scope and limits or nature and depth can profoundly vary from time to time. Relationships may also be viewed as non-negotiated unwritten contracts among people resting upon assurance of mutual help and concern in case of some need. But relationships are neither a trade nor barter. However all relationships are governed by some rules of relationship some of which may even be recognized by law. Relationships of the kind recognized by law may be called as legally determined relationships. If there is a mandatory legal procedure prescribed for constitution of a legally determined relationship, then the procedure must be complied with to constitute a legal and valid relationship.    
 What is common to all relationships is the rule that in any relationship, rules of relationship prevail over individual interest. One such rule is that in a partnership mutual interest prevails over individual interest. Companionship, love, respect etc. help sustain a relationship. But what really matters is compliance with rule of relationship whether by the sheer force of commitment or love or respect etc.
All relationships are liable to turn sour due to various reasons. One reason being that people tend to comply with relationships because of emotional reasons and ones emotional compulsions vanish or better sentimental alternatives become  available, the existing relationship turns sour.  Other important reasons are vagueness of assurance, promise or rule underlying any relationship; relationship being an undefined contract. So parties to any relationship are uncertain as to what to expect and what to deliver. Generally people don’t deal with their relationships prudently and pragmatically.
Therefore, either people are exploited in the name of relationship or lose faith in relationships. The end result is the psychological inability to establish appropriate relationship or fear of relationships. Even this is not an acceptable situation because need for relationships is an intrinsic need and one finds it difficult to lead life all alone.
Solution to the situation lies in understanding role of our relations in our emotional and physical existence, clearly understanding rules underlying different relationships and honest compliance with the rules. We should live our relationships prudently and pragmatically. Let our egocentricity or selfishness not spoil our relationships. At the same time if somebody is abusing a relationship, an exhaustive attempt should be made to make the abuser mend his ways but if the abuser is found to be incorrigible after exhaustive efforts, then a decision to end the particular relationship should be considered. Relationships should not be victims of our temper tantrums or whims and fancies. We need our relations as much as we need food, clothing and shelter, if not for material reasons, at least for our emotional wellbeing.
Author: Dr Mahesh C. Jain is a practicing medical doctor has written the book “Encounter of Science with Philosophy – A synthetic view”. The book begins with first chapter devoted to scientifically valid concept of God and then explains cosmic phenomena right from origin of nature and universe up to origin of life and evolution of man. The book includes several chapters devoted to auxiliary concepts and social sciences as corollaries to the concept of God. This is the only book which deals with origin of nature and universe from null or Zero or nothing. The book contains two chapters devoted to law and justice respectively.
Visit:http:// www.sciencengod.com
          http://curatio.in
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Monday, 4 February 2013

Can Freedom of Speech be Absolute


Can Freedom of Speech be Absolute

Summary: There has often been a demand for absolute freedom of speech from various interest groups. However scope and limits of freedom of speech and expression are limited by its constraints. Hence absolute freedom of speech and expression is only a mirage.
Absolute freedom is what we all desire. Likewise we all want to enjoy absolute freedom of speech and self expression. Therefore it is not surprising that freedom of speech and expression has been granted to us even by law.
Freedom of speech and expression has been recognized as a fundamental right in Article 19(1) of constitution of India. Freedom of speech is guaranteed not only by the constitution or statutes of various states but also by various international conventions like Universal Declaration of Human Rights, European convention on Human Rights and fundamental freedoms, International Covenant on Civil and Political Rights etc. These declarations expressly talk about protection of freedom of speech and expression.
In the judgment of the case Maneka Gandhi v. Union of India  the Supreme Court held that the freedom of speech and expression has no geographical limitation and it carries with it the right of a citizen to gather information and to exchange thought with others not only in India but abroad also.
Why to protect freedom of speech? 

Freedom of speech offers human being opportunity to express their feelings to one another, but this is not the only reason; purpose to protect the freedom of speech. There are four other reasons for freedom of speech –

1)  Discovery of truth by open discussion - According to it restrictions on speech shall prevent the ascertainment and publication of accurate facts and valuable opinion. Therefore freedom of speech is essential for social well-being. 

2) Free speech as an aspect of self- fulfillment and development – freedom of speech is an integral aspect of each individual’s right to self-development and self-fulfillment. Restriction on what we are allowed to say and write or to hear and read will hamper our personality and its growth. It helps an individual to attain self-fulfillment.

3) For expressing belief and political attitudes - freedom of speech provides opportunity to express one’s belief and show political attitudes. It ultimately results in the welfare of the society and state. Thus, freedom of speech provides a mechanism by which it would be possible to establish a reasonable balance between stability and social change.

4) For active participation in democracy – democracy is most important feature of today’s world. Freedom of speech is there to protect the right of all citizens to understand political issues so that they can participate in smooth working of democracy. That is to say, freedom of speech strengthens the capacity of an individual in participating in decision-making.

Thus we find that protection of freedom of speech is very much essential. Protection of freedom of speech is important for the discovery of truth by open discussion, for self- fulfillment and development, for expressing belief and political attitudes, and for active participation in democracy.
However, there are several restrictions to freedom of speech and expression. In British law, freedom of speech and expression is limited by legally prescribed   prohibitions.
Supreme Court in a recent judgment has held that freedom of speech and expression is "not an absolute" and remarked that journalists "should know the lakshman rekha so that they don't cross the line of contempt."

Justice Kapadia also clarified that the postponement will be for a short period of time and will not affect the trial. The doctrine, he added, has been evolved as a "preventive measure" for "administration of justice and fairness of trial" and not as a prohibitive and punitive measure.
Clause (2) of Article 19 of Indian constitution contains the grounds on which restrictions on the freedom of speech and expression can be imposed: - 

1) Security of State: Security of state is of vital importance and a government must have power to impose restriction on the activity affecting it. Under Article 19(2) reasonable restrictions can be imposed on freedom of speech and expression in the interest of security of State. However the term “security” is very crucial one. The term "security of state" refers only to serious and aggravated forms of public order e.g. rebellion, waging war against the State, insurrection, criminal acts etc.

2) Friendly relations with foreign states: The object behind the provision is to prohibit unrestrained malicious propaganda against a foreign friendly state, which may jeopardize the maintenance of good relations between India, and that state. In India, the Foreign Relations Act, (XII of 1932) provides punishment for libel by Indian citizens against foreign dignitaries.

3) Public Order: Next restriction prescribed by constitution is to maintain public order. Public order is an expression of wide connotation and signifies "that state of tranquility which prevails among the members of political society as a result of internal regulations enforced by the Government which they have established." 

4) Decency or morality: The way to express something or to say something should be decent one. It should not affect the morality of the society adversely. Sections 292 to 294 of the Indian Penal Code provide instances of restrictions on the freedom of speech and expression in the interest of decency or morality. These sections prohibit the sale or distribution or exhibition of obscene words, etc. in public places. No fix standard is laid down till now as to what is moral and indecent. The standard of morality is contextual. 

5) Contempt of Court: Indian contempt law was amended in 2006 to make “truth” a defense but with qualification that deliberate efforts to scandalize court are not exempted.
6) Defamation
7) Incitement to an offence: Obviously, freedom of speech and expression cannot confer a right to incite people to commit offence. The word 'offence' is defined as any act or omission made punishable by law for the time being in force. 

8) Sovereignty and integrity of India- To maintain sovereignty and integrity of a state freedom of speech and expression can be restricted so as not to permit any one to challenge sovereignty or to permit any one to preach something which will result in threat to integrity of the country. 

From above analysis, it is evident that Grounds contained in Article 19(2) show that they are all concerned with the national interest or in the interest of the society. The first set of grounds i.e. the sovereignty and integrity of India, the security of the State, friendly relations with foreign States and public order are all grounds referable to national interest; whereas, the second set of grounds i.e. decency, morality, contempt of court, defamation and incitement to an offence are all concerned with the interest of the society.
Similar legal situation prevails in various countries i.e. on one hand law confers freedom of speech and expression and on the other hand undermines it by imposing restrictions due to various reasons. Hence legally freedom of speech is not absolute.
We exist as independent, discrete entities in dependent and interdependent relationship with other discrete entities. No one exists in vacuum. Absolute freedom of any kind is bound to often lead to conflict situations with other independent entities existing in our ecosystem. These conflicts are likely to be a threat to our peace and tranquility. These conflicts must be avoided all the time and therefore we can exercise our freedom of speech and expression with discretion only. Indiscriminate exercise of freedom can often be detrimental to our own interest.
We all have to live as a part of a social system and no system can grant complete independence to any of its parts.
A view has been advanced that let the individuals be granted absolute freedom of speech and expression and let individual members of the society decide for themselves, whether or not they want to get along. But no uncivil means should be adopted to protest against things and events which individual members of the society find objectionable. For example M.F.Hussain should not have been made to flee the country and live in exile. I am afraid this is not an acceptable position. If M.F. Hussain had his freedom, society and its members had their freedom to have a view about his work and select the mode of protest. If M.F. Hussain was unable to appropriately regulate his creative surge then he can’t expect society to regulate its retaliatory urge and confine strictly to protest before a court of law. Uncivilized people can’t claim protection from the civilized society for their uncivil acts, means and methods. They can’t ask society to use only civil means against them.  It is an unfortunate situation but unavoidable too. One can’t demand mature civil form of protest by others when one’s hands are not clean.
Misuse of freedom of speech and expression for the purpose of mass marketing is widely rampant. Journalist, authors, painters, feature film makers and others would deliberately create and publish material only to capture mass attention by creating a controversy because they know that controversies generally sell well. They are well aware of gullibility of people and know how to exploit it to further their commercial interest. So first they commit acts injurious to interest of the society and state and then seek protection under the right to freedom of speech and expression. No civilized society can ever afford such misuse of its ideals and law.
Summing up freedom of speech and expression can’t be absolute. It is subject to several constraints. Any society is well within its rights to preemptively employ various means to enforce constraints to freedom of speech and expression.
Author: Dr Mahesh C. Jain is a practicing medical doctor and has written the book “Encounter of Science with Philosophy – A synthetic view”. The book begins with first chapter devoted to scientifically valid concept of God and then explains cosmic phenomena right from origin of nature and universe up to origin of life and evolution of man. The book includes several chapters devoted to auxiliary concepts and social sciences as corollaries to the concept of God. This is the only book which deals with origin of nature and universe from null or Zero or nothing. 
http://curatio.in
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Monday, 28 January 2013

Darwinism versus Endemic Flora and Fauna


Darwinism versus Endemic Flora and Fauna

Summary: Darwinism is the leading theory about mechanism of Biological Evolution. However facts of geographical distribution of species and varieties do not support such a view point.
Darwinism says that evolution advances by accumulation of random variations having a bearing on struggle for survival. Evolutionary divergence of populations into species and varieties is facilitated by dispersal of parental stock into large geographical area from the point of origin and subsequent isolation. According to Darwinism isolation facilitates divergence of variations along different phyletic lines leading to speciation. Therefore according to Darwinism Allopatric Speciation is the commonest mode of speciation.
Species and varieties may have cosmopolitan distribution or endemic distribution. For the cosmopolitan species and varieties it can be easily said that they originated at some point and then spread to the entire geographical area occupied by them. But generally cosmopolitan species are naturally divided into a large number of geography specific varieties on the basis of large number of definitive and deterministic variations. Variations between two different varieties of the same species can’t always be accounted for due to natural selection and struggle for survival. For example color of human skin has no bearing on human survival in different geographies, yet there are profound geography related variations. It is possible to differentiate 9 subspecies of Giraffe endemic to different areas in geographically continuous African Continent. All the variations among different varieties can’t be explained on the basis of Darwinism. http://www.wickedgiraffe.com/category/types-of-giraffe/. Most of the subspecies can be differentiated on the basis of their coat color. But it is not possible to link variations in coat color to survival of various subspecies in geographically continuous but sharply demarcated territories. If Darwinism is true then gradual variations should have occurred in accordance with some geographically identifiable gradient and should have contributed to adaptedness/adaptability of the species/variety to its ecosystem and environment.  
This is true of almost all the cosmopolitan species having large number of varieties. Geographical Indication varieties of large number of species of flora and fauna are well known. For example Darjeeling tea has its famous, naturally occurring quality and flavor only if grown in Darjeeling. Neither Darjeeling tea grown elsewhere has the same quality and flavor nor does any other tea variety grown in Darjeeling have the renowned quality and flavor. How can one relate quality and flavor of Darjeeling tea to Darwinian struggle for survival? Therefore it is self evident that all the traits of any species or variety of flora and fauna can’t to be attributed to Darwinian struggle for survival.  This includes definitive and deterministic characters which are immune from statistical variations. Hence population genetics or genetic drift can’t explain differentiating or distinctive variations among species and varieties.
Endemism is the ecological state of being unique to a defined geographic location, such as an island, nation or other defined zone, or habitat type; organisms that are indigenous to a place are not endemic to it if they are also found elsewhere. Endemic types or species are especially likely to develop on biologically isolated areas such as islands because of their geographical isolation. But endemic species with restricted geographical distribution are known to occur without any geographical isolation from the main land.
According to the World Wildlife Fund, the following ecoregions have the highest percentage of endemic plants:
·         Fynbos (South Africa)
·         Hawaiian tropical dry forests (United States)
·         Hawaiian tropical rainforests (United States)
·         Kwongan heathlands (Australia)
·         Madagascar dry deciduous forests (Madagascar)
·         Madagascar lowland forests (Madagascar)
·         New Caledonia dry forests (New Caledonia)
·         New Caledonia rain forests (New Caledonia)
·         Sierra Madre de Oaxaca pine-oak forests (Mexico)
·         Sierra Madre del Sur pine-oak forests (Mexico)
·         Luzon montane rainforests (Philippines)
·         Luzon rainforests (Philippines)
·         Luzon tropical pine forests (Philippines)
·         Mindanao montane rain forests (Philippines)
·         Mindanao-Eastern Visayas rain forests (Philippines)
·         Palawan rain forests (Philippines)
Occurrence of various endemic species in sharply defined geographical areas with or without isolation is against Darwinian gradualism over an immense period of time. In the case of unique species endemic to various islands Darwinism raises the question of source of ancestral species. No amount of dispersal, migration and isolation can explain evolution of species endemic to various islands in the world.
Hence Darwinism is unable to explain place related discontinuous, discrete, deterministic variations in flora and fauna across the globe. Organisms generally do not vary across some geographically determined gradients to which notions of continuity over immense period of time and gradualism can be applied.

  Author: Dr Mahesh C. Jain is a practicing medical doctor and has written the book “Encounter of Science with Philosophy – A synthetic view”. The book begins with first chapter devoted to scientifically valid concept of God and then explains cosmic phenomena right from origin of nature and universe up to origin of life and evolution of man. The book includes several chapters devoted to auxiliary concepts and social sciences as corollaries to the concept of God. This is the only book which deals with origin of nature and universe from null or Zero or nothing.  Chapter 30 of the book is about Evolution of Life wherein author has worked out a new theory about evolution of life.
Visit:http:// www.sciencengod.com
          http://curatio.in
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Saturday, 19 January 2013

Contradictions Inherent to Human Existence


Contradictions Inherent to Human Existence
Summary: Contradictions are inherent to human existence because of inbuilt contradictions among human needs. Contradictions give rise to conflicts and in order to keep existence, conflicts demand amicable intellectual resolution. One should not be unduly worried about contradictions and conflicts one faces in the due course of life.
We have been generally taught that food, clothing and shelter are basic human needs. It is generally assumed that satisfaction of these needs is all that is required for peaceful and happy life. This may generally be true among have nots in resource deficient environments. But among people with sufficient material resources satisfaction of these needs is insufficient to meet their ends.
All human beings besides having material and biological needs have other needs in the form of interests, sentiments and relationships.
 Interests generally refer to material goals and objectives of human living and may be rooted in other human needs for example a man in need of food is interested in getting food. Interests may also be contextual or culturally determined as generally accepted material entitlements. Interests may be protected by law and then interests are known as rights. Interests may be short term interests such as need for entertainment or long term interests such as the need to conserve relationships, carrier, business establishment, capital etc. Quite often there may be a conflict between short term interests and long term interests.
Sentiments or emotions are protective reflexes that direct action at a distance and thus have a directive influence on human needs. For example sight of the food you relish shall have a directive influence on your appetite and shall make you act to grab the food. The best case on this point is probably parental instinct leading to parental care and survival of species. Sentiments often influence our decisions regarding situations we want to get into or get away from and thus have a directive influence on our wants and desires. Sentiments are ephemeral in character, changing with changing mood, time, place etc. Sentiments may often be in conflict with long term interests.
Relationships are incidental to human need to live in groups such as family, society, work organizations etc. We have a vast variety of relationships such as father, mother, son, daughter, husband etc. Each and every relationship is unique in being governed by particular rules of relationship. In any relationship rules of the particular relationship prevail over self-interest and therefore a relationship demands commitment to rules governing the particular relationship. Relationships are long term phenomena and rules governing particular relationships generally do not vary with time and place.  Emotionally wholesome environment (entertainment) facilitates easy compliance with rules of relationship but any relationship can be satisfied only by commitment to rules of relationship. Therefore in a relationship, commitment prevails over sentiments and self-interests.
It is self-evident that human needs are diverse; therefore conflicts and contradictions are liable to arise at any point in time and space within an individual or between individuals. Short term pleasures can often be in conflict with long term prudence and pragmatism. Short term sentiments and self-interests can often run contrary to long term relationships. The opposite can also happen that for the sake of long term interests, short term needs are sacrificed. But one thing is certain that conflicts and contradictions are inherent to human existence and an individual has to relentlessly negotiate through.
Conflicts and contradictions being inherent to human condition demands provision for efficient conflict resolution mechanisms with sufficient resilience. We can’t sleep over conflicts or indulge in self-denial or self-deprivation. Conflicts often demand intellectual resolution to the greatest satisfaction of various concerns. Bullying, hegemony, self-denial, authoritarianism, self-deprivation, etc. should be avoided for the sake of mentally healthy individuals and healthy societies. Suppression of normal needs, wants and desires is not good for long term health of a society. Conflict resolution is a perpetual balancing act and we have to constantly act to keep the dynamic equilibrium, individually as well as collectively.
It demands that people adopt a life style (system of living) so that it is generally capable of meeting their short term as well as long term needs, interests, sentiments, relationships etc. Life style should be stable, progressive, well adapted to living conditions as well as adaptable to changing facts and circumstances. The life style should be capable of meeting any destabilizing influences i.e. conflicts and contradictions of diverse origin. This would also demand sufficient resilience within the system of living. So the life style is not only well adapted to living conditions but is also adaptable to future conditions. In any well organized system of living, an individual conflict or contradiction is a tiny fraction of the whole and therefore should not a cause to worry about.
There is also need to design a self-perpetuating sustainable culture which can naturally and organically take care of various human needs. It should have efficient conflict resolution mechanisms to ensure its adaptability to various challenges in the face of perpetual struggle for survival. Authoritarianism, egocentricity, will to dominate; hegemony can’t have a place in a sustainable culture.      
Lastly individuals as well as societies should not only be adapted to conditions of their existence but should also be adaptable to ever changing conditions of their existence. The issue is not existence of inherent conflicts; rather the issue is how effectively we deal with them. It demands a perpetual balancing act to sustain the dynamic equilibrium incidental to existence of an individual as well as any human society.
Author: Dr Mahesh C. Jain is a practicing medical doctor and has written the book “Encounter of Science with Philosophy – A synthetic view”. The book begins with first chapter devoted to scientifically valid concept of God and then explains cosmic phenomena right from origin of nature and universe up to origin of life and evolution of man. The book includes several chapters devoted to auxiliary concepts and social sciences as corollaries to the concept of God. This is the only book which deals with origin of nature and universe from null or Zero or nothing. 37th chapter of the book deals with Philosophy of Living.
http://curatio.in

Sunday, 13 January 2013

Origin of Life What is Wrong with RNA World Hypothesis


 Origin of Life: What is Wrong with RNA World Hypothesis

Summary: RNA world hypothesis about origin of life was based on known properties of RNA but in formulating this hypothesis, limitations of RNA as a molecule capable of independently supporting life like activities were overlooked. These limitations are pointed out and DNA is suggested as the more plausible alternative.
The phrase "RNA World" was first used by Nobel laureate Walter Gilbert in 1986, in a commentary on recent observations of the catalytic properties of various forms of RNA.
The RNA world hypothesis is supported by RNA's ability to store, transmit, and duplicate genetic information, as DNA does. RNA can act as a ribozyme, a special type of enzyme. Because it can perform the tasks of both DNA and enzymes, RNA is believed to have once been capable of supporting independent life forms. Some viruses use RNA as their genetic material, rather than DNA.
RNA world hypothesis is further supported by computational ability of RNA. All the three i.e. DNA, RNA and Peptides have been shown to possess computational ability.
 RNA computing has been used to find solutions to Knight Problem in chess. 1024 strands were used. RNA computing correctly identified 43 out of 512 possible solutions with one error. Considering very high specificity of natural biochemical reactions, error checking and correcting mechanisms must co-exist with RNA computing. This explains need for existence of antisense RNA but at the same time raises doubts about ability of RNA alone to support a living system or life like activity.
Self replicative ability of RNA is not without limitations. Only short RNA molecules have been shown to possess this ability and with a questionable fidelity.  One version, 189-bases long, had fidelity of 98.9% which would mean it would make an exact copy of an RNA molecule as long as itself in one of every eight copies. This 189 base pair ribozyme could polymerize a template of at most 14 nucleotides in length, which is too short for replication. However this level of infidelity and limitation to self replication is far too high for living systems to bear. Just a single mutation affecting just one base pair in the entire genome is known to be catastrophic, therefore the kind of self replication seen under lab conditions does not support RNA world hypothesis.
RNA is much more unstable then DNA. This inherent instability of RNA is a further limitation to the ability of RNA to account for origin of life. Living organisms keep their identity and integrity over eons of time and across a vast number of generations. With no provision for RNA repair mechanisms of the kind seen for DNA in living systems, RNA is inherently incapable of performing this task.
 Autocatalysis: Julius Rebek and his colleagues have shown that in an experimental system containing amino acid adenosine and penta fluorophenyl ester with autocatalyst Amino Adenosine triacid ester variants (AATE variants) wherein a particular AATE variant autocatalysed its own synthesis. Therefore, this experiment demonstrates that nucleic acids were not absolute necessity for initial life like activity. Autocatalytic, autoreplicative property may be regarded as one of the properties of matter. These autocatalysts can give rise to population of entities with heredity which could exhibit mutual competition. By no stretch of imagination the particular AATE variant can be regarded as living. Therefore presence of autoreplicative and autocatalyzing property is insufficient to account for origin of life.
All the properties of RNA which lend credibility to RNA world hypothesis are present in DNA but without the limitations of RNA. Moreover DNA unlike RNA is able to form much longer sequences and is much more stable then RNA (DNA has propensity to spontaneous hydrolytic cleavage @1 per million base pair per day with highly efficient DNA repair mechanisms to maintain the status quo) and thus is not only capable of keeping identity and integrity of the organism but also capable of supporting phenomenon of inheritance. Also only DNA is capable of carrying the amount of information needed to support a living system by virtue of its ability to form long sequences of nucleotide bases.
RNA world hypothesis finds some support due to existence of RNA viruses and viroids which are not dependent on DNA during their entire life cycle. But available evidence indicates that these are able to survive only within eukaryotic cells which further imply that RNA can’t account for origin of life. Since life originated about 4 billion years back whereas origin of eukaryotes has been estimated to be only 1.6 – 2.1 billion years back.
Moreover the lab conditions under which various experiments in support of RNA world hypothesis have been conducted have not been shown to naturally exist. Even the nature of chemistry demonstrated in support of RNA world hypothesis is stochastic and not definitive and deterministic. Definitive and deterministic chemistry is the hall mark of biochemistry with no room for aberrant, random, side reactions.
Therefore life could have originated only as a DNA molecule because DNA is the only molecule capable of independently supporting all life like activities.   
Author: Dr Mahesh C. Jain is a practicing medical doctor and has written the book “Encounter of Science with Philosophy – A synthetic view”. The book begins with first chapter devoted to scientifically valid concept of God and then explains cosmic phenomena right from origin of nature and universe up to origin of life and evolution of man. The book includes several chapters devoted to auxiliary concepts and social sciences as corollaries to the concept of God. This is the only book which deals with origin of nature and universe from null. Twenty-ninth chapter of the book deals with the subject matter of ‘Origin of Life’.
http://curatio.in
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